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1.
Braz. j. phys. ther. (Impr.) ; 19(3): 186-193, May-Jun/2015. tab, graf
Article in English | LILACS | ID: lil-751383

ABSTRACT

Background: Risk of falls increases as age advances. Complaints of impaired balance are very common in the elderly age group. Objectives: The objective of this study was to investigate whether the subjective perception of impaired balance was associated with deficits in postural control (objective analysis) in elderly community-dwelling women. Method: Static posturography was used in two groups: elderly women with (WC group) and without (NC group) complaints of impaired balance. The area, mean sway amplitude and mean speed of the center of pressure (COP) in the anterior-posterior (AP) and medial-lateral (ML) directions were analyzed in three stances: single-leg stance, double-leg stance and tandem stance, with eyes open or closed on two different surfaces: stable (firm) and unstable (foam). A digital chronometer was activated to measure the time limit (Tlimit) in the single-leg stance. Kruskal-Wallis tests followed by Mann-Whitney tests, Friedman analyses followed by post hoc Wilcoxon tests and Bonferroni corrections, and Spearman statistical tests were used in the data analysis. Differences of p<0.05 were considered statistically significant. Results: The results of posturography variables revealed no differences between groups. The timed single-leg stance test revealed a shorter Tlimit in the left single-leg stance (p=0.01) in WC group compared to NC group. A negative correlation between posturography variables and Tlimit was detected. Conclusions: Posturography did not show any differences between the groups; however, the timed single-leg stance allowed the authors to observe differences in postural control performance between elderly women with and those without complaints of impaired balance. .


Subject(s)
Animals , Facial Bones/embryology , Microscopy, Confocal/methods , Zebrafish/embryology , Animals, Genetically Modified , Craniofacial Abnormalities/genetics , Morphogenesis/genetics , Morphogenesis/physiology , Neural Crest/embryology , Receptor, Platelet-Derived Growth Factor alpha/genetics , Receptors, G-Protein-Coupled/genetics , /genetics , Time-Lapse Imaging/methods , Zebrafish Proteins/genetics , Zebrafish/genetics
2.
Invest. clín ; 29(4): 175-94, 1988. ilus, tab
Article in Spanish | LILACS | ID: lil-71588

ABSTRACT

El síndrome malformativo de la holoprosencefalia (arrinencefalia), caracterizado por anomalías de variable severidad de cerebro y cara, es consecuencia de la morfogénesis incompleta del prosencéfalo y un déficit en el desarrollo de la línea medio-facial. En su etiopatogenia se han incriminado factores genéticos, tóxicos, metabólicos, infecciosos y parasitarios. Describimos 6 casos de autopsia estudiados en el Hospital "Dr. Adolfo Pons", IVSS, de Maracaibo, durante el período 1984-1987. La incidencia general de la malformación para 12.878 nacimientos fue de 0,04%. La edad materna promedio fue de 23 años. La serie se caracterizó por un espectro malformativo cerebro-facial proteiforme: 4 casos correspondieron a malformación cerebral severa, tipo holoprosencefalia alobar en 3 y semilobar en 1. Los encéfalos compartieron las siguientes características: falta de desarrollo de ambos hemiferios cerebrales, ausencia del cuerpo calloso, septum pellucidum y pilares anteriores del fornix, fusión de extructuras diencefálicas y aplasia olftoria. La malformación facial correspondió en 2 casos al tipo III de las categorías de DeMyer (Cebocefalia), nacidos de una misma madre en un mismo año, en otros 2 correspondió al tipo V (labio hendido lateral). Hubo un caso tipo I (ciclopia) y otro tipo IV (labio hendido media). A los casos de aplasia olfatiria (Holoprosencefalia lobar), se asociaron hidrocefalia por estenosis de acueducto de Silvio, bazo accesorio y/o fusión pancreato-esplénica, displasia suprarrenal, estenosis ureteral, vagina doble y polidactilia, anomalias que suguieren alteraciones cromosócas..


Subject(s)
Infant, Newborn , Humans , Male , Female , Cerebrum/abnormalities , Chromosome Aberrations/genetics , Facial Bones/embryology
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